Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915602 | 0.81 | ALDH1A1 (0.60) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL16426670 | 0.81 | MAPT (0.51) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL6861634 | 0.79 | ALDH1A1 (0.77) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL25259478 | 0.70 | ALDH1A1 (0.73) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL1914959 | 0.70 | ALDH1A1 (0.60) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL1915536 | 0.70 | ALDH1A1 (0.60) | MAPTKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL31114407 | 0.70 | ALDH1A1 (0.73) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL1915756 | 0.69 | ALDH1A1 (0.62) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL1914731 | 0.69 | ALDH1A1 (0.62) | MAPTKDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL1915954 | 0.68 | MAPT (0.66) | MAPTKDM4EGAARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF ALBANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | TARBP1, AARS1, NSUN3 | MAPT 4117/4885KDM4E 2123/4885GAA 1464/4885 |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | TARBP1, AARS1, NSUN3 | MAPT 4117/4885KDM4E 2123/4885GAA 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.