Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899112 | 0.89 | ALDH1A1 (0.83) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL1915602 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL5576161 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL17899118 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL5574964 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL5574960 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL5574968 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL17899117 | 0.79 | MAPT (0.56) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL16426670 | 0.78 | MAPT (0.51) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL1915536 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452590-A1 | STEREOSTRUCTURE OF DNA RECOMBINATION REPAIR ENZYME AND UTILIZATION THEREOF | Riken (JP) | 2004-09-01 | — | — | EP | disclosed |