SCHEMBL17899153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17899409	0.88	PARP10 (0.39)	PARP10PARP14OPRM1OPRD1OPRK1
	SCHEMBL21697468	0.86	SLC6A4 (0.39)	PARP10PARP14MAPTSLC6A2SLC6A4
	SCHEMBL17888562	0.85	PARP14 (0.35)	PARP10PARP14OPRM1OPRD1OPRK1
	SCHEMBL17931450	0.83	ACACB (0.39)	PARP10PARP14OPRM1OPRD1OPRK1
	SCHEMBL17899389	0.83	MAPK1 (0.37)	PARP10PARP14OPRM1OPRD1OPRK1
	SCHEMBL17899395	0.83	KMT2A (0.46)	PARP10PARP14MAPTPARP15ALDH1A1
	SCHEMBL17888639	0.80	PARP14 (0.38)	PARP10PARP14OPRM1OPRD1OPRK1
	SCHEMBL17899406	0.78	PARP10 (0.44)	PARP10PARP14OPRM1OPRD1OPRK1
	SCHEMBL17888577	0.77	PARP1 (0.36)	PARP10PARP14MAPTPARP15ALDH1A1
	SCHEMBL17888610	0.76	MEN1 (0.41)	OPRM1OPRD1OPRK1KMT2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.