Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899773 | 0.91 | NPSR1 (0.40) | NPSR1NPC1RAB9ARAPGEF4HSD17B3 | |
| SCHEMBL15381073 | 0.89 | NPSR1 (0.44) | NPSR1NPC1RAB9APARP10PARP11 | |
| SCHEMBL12367737 | 0.88 | HPGD (0.47) | NPSR1NPC1RAB9ARAPGEF4HSD17B3 | |
| SCHEMBL23225689 | 0.87 | PARP10 (0.53) | NPC1RAB9APARP10PARP11FYN | |
| SCHEMBL12653254 | 0.84 | HPGD (0.49) | NPSR1NPC1RAB9ARAPGEF4HSD17B3 | |
| SCHEMBL12653575 | 0.82 | ALDH1A1 (0.50) | NPSR1NPC1RAB9ACNR1CYP11B1 | |
| SCHEMBL12620097 | 0.80 | NPSR1 (0.41) | NPSR1NPC1RAB9ARAPGEF4MAPK14 | |
| SCHEMBL20079881 | 0.77 | CYP11B1 (0.52) | NPC1RAB9APARP10PARP11HSD17B3 | |
| SCHEMBL12619710 | 0.77 | HSD17B1 (0.43) | NPC1RAB9APARP10PARP11FYN | |
| SCHEMBL20755526 | 0.77 | CNR1 (0.45) | NPC1RAB9ACLK4CNR1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272894-B1 | POLYMER COMPOUND, RETICULATED POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING | MITSUBISHI CHEM CORP (JP) | 2016-07-06 | — | — | EP | disclosed |