Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.37 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367737 | 0.94 | HPGD (0.47) | NPSR1HPGDRAPGEF4NPC1RAB9A | |
| SCHEMBL12653254 | 0.93 | HPGD (0.49) | NPSR1HPGDRAPGEF4NPC1RAB9A | |
| SCHEMBL17899771 | 0.91 | NPSR1 (0.47) | NPSR1RAPGEF4NPC1RAB9ANFKB1 | |
| SCHEMBL21808588 | 0.85 | HPGD (0.52) | NPSR1HPGDRAPGEF4NPC1RAB9A | |
| SCHEMBL12620097 | 0.83 | NPSR1 (0.41) | NPSR1HPGDRAPGEF4NPC1RAB9A | |
| SCHEMBL15381071 | 0.83 | CCR5 (0.39) | NPSR1HPGDRAPGEF4NPC1RAB9A | |
| SCHEMBL12653575 | 0.82 | ALDH1A1 (0.50) | NPSR1HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL22815330 | 0.82 | HPGD (0.55) | NPSR1HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL15381073 | 0.80 | NPSR1 (0.44) | NPSR1HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL20755526 | 0.80 | CNR1 (0.45) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272894-B1 | POLYMER COMPOUND, RETICULATED POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING | MITSUBISHI CHEM CORP (JP) | 2016-07-06 | — | — | EP | disclosed |