Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDNF | P23560 | 3/20 | 0.41 |
| ▸ | PTN | P21246 | 2/20 | 0.41 |
| ▸ | MDK | P21741 | 2/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 7/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.37 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965622 | 0.90 | LGALS3 (0.49) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| SCHEMBL25768039 | 0.90 | LGALS3 (0.49) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| SCHEMBL9885112 | 0.85 | LGALS3 (0.39) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| SCHEMBL13649137 | 0.85 | LGALS3 (0.39) | LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8 | |
| SCHEMBL15429218 | 0.84 | BDNF (0.41) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| SCHEMBL13483313 | 0.82 | LGALS3 (0.51) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| SCHEMBL27433376 | 0.82 | LGALS3 (0.51) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| Dermatan SCHEMBL18232151 | 0.81 | LGALS3 (0.49) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| Dermatan SCHEMBL13472480 | 0.81 | LGALS3 (0.49) | BDNFPTNMDKLGALS3LGALS7; LGALS7B | |
| Dermatan SCHEMBL16311126 | 0.81 | LGALS3 (0.49) | BDNFPTNMDKLGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841462-B1 | CROSSLINKED HYALURONAN DERIVATIVE, METHOD OF PREPARATION THEREOF, HYDROGEL AND MICROFIBERS BASED THEREON | CONTIPRO PHARMA A S (CZ) | 2016-07-06 | — | — | EP | disclosed |
| US-9062044-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2015-06-23 | — | — | US | disclosed |