Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 7/20 | 0.49 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.47 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.46 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTN | P21246 | 1/20 | 0.41 |
| ▸ | MDK | P21741 | 1/20 | 0.41 |
| ▸ | BDNF | P23560 | 1/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25768039 | 1.00 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| SCHEMBL17899826 | 0.90 | BDNF (0.41) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL19184706 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL19846466 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL12691925 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL29360360 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL16311126 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL13472480 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| Dermatan SCHEMBL18232151 | 0.90 | LGALS3 (0.49) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 | |
| SCHEMBL19675783 | 0.89 | MAPK1 (0.57) | LGALS3LGALS7; LGALS7BLGALS1LGALS8LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389661-B2 | Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs | ADOCIA (FR) | 2013-03-05 | — | — | US | disclosed |
| US-8241620-B2 | Complex polymere amphiphile-PDGF | ADOCIA (FR) | 2012-08-14 | — | — | US | disclosed |
| US-20110301086-A1 | Complex polymere amphiphile-PDGF | ADOCIA (FR) | 2011-12-08 | — | — | US | disclosed |
| US-20100190709-A1 | Angiogenic composition | ADOCIA (FR) | 2010-07-29 | — | — | US | disclosed |
| US-20090221805-A1 | Complex polymere amphiphile-PDGF | PROTEINS AND PEPTIDES MANAGEMENT (FR) | 2009-09-03 | — | — | US | disclosed |
| US-20090048412-A1 | Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs | ADOCIA (FR) | 2009-02-19 | — | — | US | disclosed |
| US-20080293635-A1 | Angiogenic composition | ADOCIA (FR) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190709-A1 | Angiogenic composition | PDGFA, PGF, VEGFA | LGALS3 745/4885LGALS7; LGALS7B 1816/4885LGALS1 961/4885 |
| US-20110301086-A1 | Complex polymere amphiphile-PDGF | PDGFA, PDGFRA, FIBP | LGALS3 1827/4885LGALS7; LGALS7B 2089/4885LGALS1 2072/4885 |
| US-20090221805-A1 | Complex polymere amphiphile-PDGF | PDGFA, PDGFRA, FIBP | LGALS3 1827/4885LGALS7; LGALS7B 2089/4885LGALS1 2072/4885 |
| US-20080293635-A1 | Angiogenic composition | PDGFA, PGF, VEGFA | LGALS3 745/4885LGALS7; LGALS7B 1816/4885LGALS1 961/4885 |
| US-20090048412-A1 | Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs | BMP2, BMP1, BMP6 | LGALS3 329/4885LGALS7; LGALS7B 372/4885LGALS1 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.