Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169441 | 0.92 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL29506888 | 0.92 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL25917160 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL2521660 | 0.85 | MAPT (0.65) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL2526976 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL26632884 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL26736125 | 0.83 | ALOX5 (0.55) | ALDH1A1KDM4EALOX5GAAHSD17B10 | |
| SCHEMBL28434093 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL2523778 | 0.82 | HPGD (0.56) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL8257094 | 0.82 | CNR1 (0.56) | ALDH1A1KDM4EHPGDTDP1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10173990-B2 | URAT1 inhibitor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20170290795-A1 | URAT1 INHIBITOR | J-PHARMA CO., LTD. (JP) | 2017-10-12 | — | — | US | disclosed |
| US-20170290795-A1 | URAT1 INHIBITOR | J-PHARMA CO., LTD. (JP) | 2017-10-12 | — | — | US | disclosed |
| WO-2016108282-A1 | URAT1 INHIBITOR | 日本ケミファ株式会社 | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290795-A1 | URAT1 INHIBITOR | SLC10A1, XDH, URB2 | ALDH1A1 673/4885KDM4E 2799/4885HPGD 4581/4885 |
| US-10173990-B2 | URAT1 inhibitor | SLC10A1, XDH, URB2 | ALDH1A1 672/4885KDM4E 2791/4885HPGD 4601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.