Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17893679 | 0.89 | FFAR4 (0.48) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14117684 | 0.83 | RAB9A (0.57) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL7014268 | 0.82 | HSD17B10 (0.45) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14117662 | 0.81 | LGMN (0.54) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14337144 | 0.78 | LGMN (0.47) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14336803 | 0.78 | CHRM2 (0.48) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL12684501 | 0.77 | MAPK8 (0.41) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL17893792 | 0.77 | ADRB1 (0.53) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4554831 | 0.76 | LGMN (0.63) | LGMNALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL17893619 | 0.75 | LGMN (0.44) | LGMNALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107832-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINES AND TETRAHYDROPYRIDOPYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2016-07-07 | — | — | WO | disclosed |