Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | NMT2 | O60551 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | NMT1 | P30419 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144592 | 0.89 | GPR35 (0.58) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL25669938 | 0.85 | GPR35 (0.54) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL13243279 | 0.84 | GPR35 (0.49) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL115378 | 0.83 | GPR35 (0.52) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL115418 | 0.83 | GPR35 (0.52) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL13243180 | 0.82 | GPR35 (0.39) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL116735 | 0.80 | GPR35 (0.66) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL143979 | 0.80 | GPR35 (0.72) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL21556363 | 0.78 | GPR35 (0.55) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL25472684 | 0.76 | GPR35 (0.62) | GPR35LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058049-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2012-03-08 | — | — | US | disclosed |
| WO-2010088455-A2 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION (US) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058049-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | CLN6, CA6, GALNT6 | GPR35 699/4885LMNA 186/4885TDP1 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.