SCHEMBL17905296

SCHEMBL17905296

CCC[C@@H](OCc1ccccc1)[C@H](C)OC(=O)[C@H](C)NC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 1/20 0.47
▸ CTSK P43235 5/20 0.44
▸ PPARA Q07869 1/20 0.44
▸ CTSS P25774 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ CTSL P07711 1/20 0.42
▸ ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17896173 0.85 PPARA (0.43) SYKCTSKPPARACTSSMAPT
SCHEMBL17905295 0.85 PPARA (0.43) SYKCTSKPPARACTSSMAPT
SCHEMBL17906532 0.85 CTSK (0.43) SYKCTSKCTSSMAPTATM
SCHEMBL17901511 0.83 ATM (0.48) SYKCTSKCTSSCTSLATM
SCHEMBL17901295 0.81 PPARA (0.49) SYKCTSKPPARACTSSMAPT
SCHEMBL20682996 0.81 PPARA (0.49) SYKCTSKPPARACTSSMAPT
SCHEMBL20682879 0.81 CTSK (0.46) SYKCTSKCTSSMAPTATM
SCHEMBL17901218 0.81 CTSK (0.46) SYKCTSKCTSSMAPTATM
SCHEMBL17901224 0.81 CTSK (0.46) SYKCTSKCTSSMAPTATM
SCHEMBL17901034 0.81 CTSK (0.46) SYKCTSKCTSSMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10433555-B2 Picolinamide compounds with fungicidal activity DOW AGROSCIENCES LLC (US) 2019-10-08 — — US disclosed
WO-2016109289-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed
WO-2016109288-A1 USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10433555-B2 Picolinamide compounds with fungicidal activity PFAS, CASP2, CYP1A2 SYK 4809/4885CTSK 2808/4885PPARA 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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