Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.71 |
| ▸ | PRKCG | P05129 | 1/20 | 0.71 |
| ▸ | PRKCB | P05771 | 1/20 | 0.71 |
| ▸ | PRKCA | P17252 | 1/20 | 0.71 |
| ▸ | PRKCH | P24723 | 1/20 | 0.71 |
| ▸ | PRKCI | P41743 | 1/20 | 0.71 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.71 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.71 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.71 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371353 | 0.91 | LMNA (0.64) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL10645725 | 0.91 | LMNA (0.64) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL2525610 | 0.91 | LMNA (0.64) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL8874191 | 0.89 | MAPK1 (0.54) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL30928 | 0.88 | AKT1 (0.81) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL10755721 | 0.88 | AKT1 (0.81) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL2237831 | 0.88 | ALDH1A1 (0.70) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL2231020 | 0.88 | ALDH1A1 (0.70) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL93895 | 0.88 | ALDH1A1 (0.70) | AKT1LMNAALDH1A1PRKD3PRKCG | |
| SCHEMBL93768 | 0.88 | ALDH1A1 (0.70) | AKT1LMNAALDH1A1PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221453-B2 | Advanced detection of sepsis | BECTON, DICKINSON AND COMPANY (US) | 2019-03-05 | — | — | US | disclosed |
| US-20180305758-A1 | ADVANCED DETECTION OF SEPSIS | BECTON DICKINSON CO (US) | 2018-10-25 | — | — | US | disclosed |
| US-9885084-B2 | Advanced detection of sepsis | BECTON, DICKINSON AND COMPANY (US) | 2018-02-06 | — | — | US | disclosed |
| US-20180002752-A1 | ADVANCED DETECTION OF SEPSIS | BECTON DICKINSON CO (US) | 2018-01-04 | — | — | US | disclosed |
| US-9708661-B2 | Advanced detection of sepsis | BECTON, DICKINSON AND COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160040233-A1 | ADVANCED DETECTION OF SEPSIS | BECTON DICKINSON CO (US) | 2016-02-11 | — | — | US | disclosed |
| US-9091698-B2 | Advanced detection of sepsis | BECTON, DICKINSON AND COMPANY (US) | 2015-07-28 | — | — | US | disclosed |
| US-20140302533-A1 | ADVANCED DETECTION OF SEPSIS | BECTON, DICKINSON AND COMPANY (US) | 2014-10-09 | — | — | US | disclosed |
| US-8669113-B2 | Advanced detection of sepsis | BECTON, DICKINSON AND COMPANY (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120301910-A1 | DETECTION OF LYSOPHOSPHATIDYLCHOLINE FOR PROGNOSIS OR DIAGNOSIS OF A SYSTEMIC INFLAMMATORY CONDITION | BECTON, DICKINSON AND COMPANY (US) | 2012-11-29 | — | — | US | disclosed |
| US-8183050-B2 | Detection of lysophosphatidylcholine for prognosis or diagnosis of a systemic inflammatory condition | BECTON, DICKINSON AND COMPANY (US) | 2012-05-22 | — | — | US | disclosed |
| US-20110118569-A1 | Advanced Detection of Sepsis | BECTON, DICKINSON AND COMPANY | 2011-05-19 | — | — | US | disclosed |
| EP-1940231-B1 | DETECTION OF LYSOPHOSPHATIDYLCHOLINE FOR PROGNOSIS OR DIAGNOSIS OF A SYSTEMIC INFLAMMATORY CONDITION | BECTON DICKINSON CO (US) | 2011-05-04 | — | — | EP | disclosed |
| US-20070111316-A1 | Detection of lysophosphatidylcholine for prognosis or diagnosis of a systemic inflammatory condition | BECTON, DICKINSON AND COMPANY | 2007-05-17 | — | — | US | disclosed |