Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | AKT1 | P31749 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | GMNN | O75496 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | PRKCG | P05129 | 1/20 | 0.64 |
| ▸ | PRKCB | P05771 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 1/20 | 0.64 |
| ▸ | PRKCH | P24723 | 1/20 | 0.64 |
| ▸ | PRKCI | P41743 | 1/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.64 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.64 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645725 | 1.00 | LMNA (0.64) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL2525610 | 1.00 | LMNA (0.64) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL8110225 | 0.92 | ALDH1A1 (0.63) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL1790701 | 0.91 | AKT1 (0.71) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL8874191 | 0.89 | MAPK1 (0.54) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL10755721 | 0.88 | AKT1 (0.81) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL30928 | 0.88 | AKT1 (0.81) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL2237831 | 0.88 | ALDH1A1 (0.70) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL93895 | 0.88 | ALDH1A1 (0.70) | LMNAMAPK1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL2231020 | 0.88 | ALDH1A1 (0.70) | LMNAMAPK1AKT1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9164108-B2 | Liposome-based microarray and methods of use thereof | SRI INTERNATIONAL (US) | 2015-10-20 | — | — | US | disclosed |
| US-20090274579-A1 | Methods and devices for controlled monolayer formation | NANOXIS AB (SE) | 2009-11-05 | — | — | US | disclosed |
| US-20070059765-A1 | Liposome-based microarray and methods of use thereof | STEINMAN, LAWRENCE | 2007-03-15 | — | — | US | disclosed |
| WO-2006102687-A1 | A LIPOSOME-BASED MICROARRAY AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-09-28 | — | — | WO | disclosed |
| US-5661013-A | CULTURING PENICILLIUM RUBRUM STRAIN; ANTIINFLAMMATORY AGENT | NOVO NORDISK A/S (DK) | 1997-08-26 | — | — | US | disclosed |
| WO-1996040635-A1 | NOVEL 5-HYDROXYPYRROLIDONE-2 DERIVATIVES ISOLATED FROM CERTAIN STRAINS OF PENICILLIUM AND SCLEROPHOMA AND THEIR USE AS PAF SYNTHESIS MODULATORS | ZYMOGENETICS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5550148-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS | ZYMOGENETICS, INC. (US) | 1996-08-27 | — | — | US | disclosed |