Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 11/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808661 | 0.90 | TTR (0.64) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL68189 | 0.84 | TTR (0.83) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL17819836 | 0.84 | CSNK2A1 (0.50) | TTRKDM4EMEN1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL11749391 | 0.83 | TTR (0.81) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL16377338 | 0.82 | ROCK2 (0.60) | TTRPARP1CSNK2A1ROCK2 | |
| SCHEMBL11322640 | 0.82 | TTR (0.80) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL1787556 | 0.80 | TTR (1.00) | TTRKDM4EMEN1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL11367851 | 0.79 | TTR (0.97) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL28458382 | 0.78 | KMT2A (0.55) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL30593476 | 0.78 | KMT2A (0.55) | KDM4EALDH1A1HPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |