SCHEMBL17907277

SCHEMBL17907277

Cc1cc(C(C)(C)C)c(-c2c(C(C)(C)C)[c]ccc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
HSPA5 P11021 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2903858 0.77 CA2 (0.33) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL10890116 0.76 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL11381686 0.76 CNR2 (0.40)
SCHEMBL9423241 0.73 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL5052023 0.70 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1CA2TYRCYP2C9
SCHEMBL10892431 0.70 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL26976671 0.69 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL10893346 0.69 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL855717 0.69 CA2 (0.30) CA2
SCHEMBL28311512 0.68 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042980-A1 THERMOPLASTIC RESIN COMPOSITION, RESIN MOLDED ARTICLE, AND METHOD FOR PRODUCING PLATING-LAYER-EQUIPPED RESIN MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2016-07-13 EP disclosed