SCHEMBL5052023

SCHEMBL5052023

CC(C)(C)c1[c]ccc(C(C)(C)C)c1-c1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
ALOX15 P16050 2/20 0.44
CYP2C9 P11712 2/20 0.44
NR1I2 O75469 1/20 0.44
LMNA P02545 1/20 0.44
MIF P14174 1/20 0.44
TYR P14679 1/20 0.44
HTT P42858 1/20 0.44
NFE2L2 Q16236 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RARB P10826 2/20 0.41
RARG P13631 2/20 0.41
CYP1A2 P05177 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
ATP2A2 P16615 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATP2A3 Q93084 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1176397 0.75 ALDH1A1 (0.67) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL31146788 0.75 ALDH1A1 (0.67) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL5692411 0.74 ALDH1A1 (0.55) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL17907277 0.70 SMN1; SMN2 (0.39) ALDH1A1CYP2C9TYRSMN1; SMN2CA2
SCHEMBL9158392 0.70 CA2 (0.48) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL2721125 0.69 ALDH1A1 (0.69) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL1237149 0.69 ALDH1A1 (0.69) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL16581393 0.69 ALDH1A1 (0.57) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL10910263 0.68 RARB (0.57) ALDH1A1ALOX15CYP2C9NR1I2LMNA
SCHEMBL3565632 0.67 ALOX5 (0.57) ALDH1A1ALOX15CYP2C9NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080317987-A1 Nanocomposite materials for ethanol, methanol and hydrocarbon transportation use and storage GLEN BURNIE TECHNOLOGIES, LLC 2008-12-25 US claimed