Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907900 | 0.90 | TP53 (0.33) | MEN1KMT2A | |
| SCHEMBL17907902 | 0.89 | NPC1 (0.39) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL978460 | 0.77 | MEN1 (0.45) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL17907903 | 0.76 | TRPV1 (0.33) | — | |
| SCHEMBL14263446 | 0.75 | AR (0.57) | AR | |
| SCHEMBL26265751 | 0.73 | MAPT (0.36) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL979841 | 0.72 | AR (0.54) | AR | |
| SCHEMBL979554 | 0.67 | AR (0.54) | AR | |
| SCHEMBL26423009 | 0.65 | BRD4 (0.41) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL19663767 | 0.63 | ALDH1A1 (0.35) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756109-B1 | NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | claimed |
| EP-1756109-B1 | NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | disclosed |