Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907902 | 0.78 | NPC1 (0.39) | — | |
| SCHEMBL17907900 | 0.77 | TP53 (0.33) | — | |
| SCHEMBL17907901 | 0.76 | MEN1 (0.39) | — | |
| SCHEMBL26265751 | 0.72 | MAPT (0.36) | — | |
| SCHEMBL26423009 | 0.63 | BRD4 (0.41) | — | |
| SCHEMBL19663767 | 0.62 | ALDH1A1 (0.35) | — | |
| SCHEMBL17907899 | 0.61 | AR (0.37) | — | |
| SCHEMBL21035092 | 0.60 | IDO1 (0.57) | — | |
| SCHEMBL30189253 | 0.59 | KDM4E (0.47) | — | |
| SCHEMBL831575 | 0.59 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756109-B1 | NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | claimed |
| EP-1756109-B1 | NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | disclosed |