Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907901 | 0.90 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL17907902 | 0.90 | NPC1 (0.39) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17907903 | 0.77 | TRPV1 (0.33) | — | |
| SCHEMBL979841 | 0.76 | AR (0.54) | — | |
| SCHEMBL26265751 | 0.74 | MAPT (0.36) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL978460 | 0.66 | MEN1 (0.45) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL26423009 | 0.66 | BRD4 (0.41) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL14543247 | 0.65 | CA2 (0.38) | MAPTMEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL19663767 | 0.64 | ALDH1A1 (0.35) | MAPTMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14377042 | 0.63 | MEN1 (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756109-B1 | NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | claimed |
| EP-1756109-B1 | NOVEL INDOLE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | disclosed |