SCHEMBL17911909

SCHEMBL17911909

COC(=O)C(CN)NS(=O)(=O)c1c(C)cc(OCCCC(=O)NCCNC(=O)OCc2ccccc2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP2 P08253 6/20 0.42
MMP9 P14780 6/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 1/20 0.41
ADAM10 O14672 3/20 0.41
ADAM17 P78536 3/20 0.41
MMP14 P50281 2/20 0.41
TAAR1 Q96RJ0 1/20 0.40
MMP1 P03956 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24136485 1.00 CA1 (0.42) CA1CA2MMP2MMP9L3MBTL1
SCHEMBL8313275 1.00 CA1 (0.42) CA1CA2MMP2MMP9L3MBTL1
Trifluoroacetic Acid SCHEMBL2274359 0.95 L3MBTL1 (0.41) CA1CA2MMP2MMP9L3MBTL1
SCHEMBL4653743 0.95 SMN1; SMN2 (0.42) CA1CA2MMP2MMP9L3MBTL1
SCHEMBL14271452 0.95 SMN1; SMN2 (0.42) CA1CA2MMP2MMP9L3MBTL1
SCHEMBL4960020 0.94 MMP2 (0.47) MMP2MMP9L3MBTL1HPGDMAPT
SCHEMBL19809645 0.94 MMP2 (0.47) MMP2MMP9L3MBTL1HPGDMAPT
SCHEMBL12372106 0.93 L3MBTL1 (0.44) CA1CA2MMP2MMP9L3MBTL1
SCHEMBL12372083 0.91 MMP2 (0.42) CA1CA2MMP2MMP9L3MBTL1
SCHEMBL4385496 0.90 L3MBTL1 (0.40) MMP2MMP9L3MBTL1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250009915-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM CORPORATION (JP) 2025-01-09 US disclosed
EP-4249471-A2 PHARMACEUTICAL COMPOSITION OF A NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM Corporation (JP) 2023-09-27 EP disclosed
EP-3929196-B1 PHARMACEUTICAL COMPOSITION OF A NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM CORP (JP) 2023-08-23 EP disclosed
US-20230136073-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-11426473-B2 Nitrogen-containing compound or salt thereof, or metal complex thereof FUJIFILM CORPORATION (JP) 2022-08-30 US disclosed
EP-3929196-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM Corporation (JP) 2021-12-29 EP disclosed
EP-3050878-B1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM CORP (JP) 2021-10-27 EP disclosed
EP-3050878-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF Fujifilm Corporation (JP) 2016-08-03 EP disclosed
US-20160199520-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230136073-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF SLC39A3, SLC39A14, SLC39A11 CA1 111/4885CA2 185/4885MMP2 3743/4885
US-20160199520-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF SLC39A3, SLC39A14, SLC39A11 CA1 118/4885CA2 188/4885MMP2 3778/4885
US-11426473-B2 Nitrogen-containing compound or salt thereof, or metal complex thereof SLC39A3, SLC39A14, SLC39A11 CA1 105/4885CA2 184/4885MMP2 3963/4885
US-20250009915-A1 NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF SLC39A3, SLC39A14, SLC39A11 CA1 118/4885CA2 188/4885MMP2 3778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.