Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 6/20 | 0.39 |
| ▸ | MMP9 | P14780 | 6/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911909 | 0.95 | CA1 (0.42) | L3MBTL1MAPTCA1CA2MMP2 | |
| SCHEMBL24136485 | 0.95 | CA1 (0.42) | L3MBTL1MAPTCA1CA2MMP2 | |
| SCHEMBL8313275 | 0.95 | CA1 (0.42) | L3MBTL1MAPTCA1CA2MMP2 | |
| Trifluoroacetic Acid SCHEMBL27589878 | 0.95 | ITGB3 (0.44) | L3MBTL1MAPTITGB3ITGA2BMMP2 | |
| Trifluoroacetic Acid SCHEMBL4385494 | 0.95 | ITGB3 (0.44) | L3MBTL1MAPTITGB3ITGA2BMMP2 | |
| SCHEMBL4385496 | 0.92 | L3MBTL1 (0.40) | L3MBTL1MAPTITGB3ITGA2BMMP2 | |
| SCHEMBL4653743 | 0.92 | SMN1; SMN2 (0.42) | L3MBTL1MAPTCA1CA2MMP2 | |
| SCHEMBL14271452 | 0.92 | SMN1; SMN2 (0.42) | L3MBTL1MAPTCA1CA2MMP2 | |
| SCHEMBL4960020 | 0.90 | MMP2 (0.47) | L3MBTL1MAPTITGB3ITGA2BMMP2 | |
| SCHEMBL19809645 | 0.90 | MMP2 (0.47) | L3MBTL1MAPTITGB3ITGA2BMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998462-B2 | Linkers for anchoring targeting ligands | KEREOS, INC. (US) | 2011-08-16 | — | — | US | disclosed |