Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991457 | 0.97 | PHGDH (0.39) | PHGDHMGLLFAAHALDH1A1 | |
| SCHEMBL27823420 | 0.87 | — | — | |
| SCHEMBL40978 | 0.77 | PHGDH (0.56) | PHGDHMGLLFAAHALDH1A1LMNA | |
| SCHEMBL27874517 | 0.75 | ALOX5 (0.43) | PHGDHALDH1A1FDPSADH1AALOX5 | |
| SCHEMBL27571128 | 0.73 | PHGDH (0.59) | PHGDHMGLLFAAHALDH1A1LMNA | |
| SCHEMBL4336162 | 0.72 | NOS2 (0.42) | PHGDHALOX5 | |
| SCHEMBL14538277 | 0.72 | ALOX5 (0.41) | FDPSADH1AALOX5EPHX1ADH1C | |
| SCHEMBL15259538 | 0.71 | PHGDH (0.40) | PHGDHMGLLFAAHALDH1A1LMNA | |
| SCHEMBL10780617 | 0.71 | EPHX1 (0.37) | PHGDHALDH1A1LMNAFDPSADH1A | |
| SCHEMBL27828541 | 0.70 | ALOX5 (0.40) | FDPSADH1AALOX5EPHX1ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | claimed |
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | disclosed |