Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817926 | 1.00 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| SCHEMBL24855995 | 0.93 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| SCHEMBL24855527 | 0.87 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| SCHEMBL29752123 | 0.85 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| SCHEMBL179136 | 0.85 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| SCHEMBL29914670 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL11188554 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| Hydrochloric Acid SCHEMBL564874 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29361270 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYP1B1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11766454 | 0.83 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTKDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360088-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-31 | — | — | US | disclosed |
| EP-4367104-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | Oregon Health & Science University (US) | 2024-05-15 | — | — | EP | disclosed |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | UNIV OREGON HEALTH & SCIENCE (US) | 2023-03-30 | — | — | US | disclosed |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | UNIV OREGON HEALTH & SCIENCE (US) | 2023-03-30 | — | — | US | disclosed |
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-03-30 | — | — | US | disclosed |
| WO-2023278874-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023278874-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-05 | — | — | WO | disclosed |
| EP-4084829-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | Oregon Health & Science University (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021158820-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021158820-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021138116-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-08 | — | — | WO | disclosed |
| WO-2021138116-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | GAP43, NTRK1, MAG | ALDH1A1 861/4885L3MBTL1 2295/4885CYP1B1 3921/4885 |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | ALDH1A1 556/4885L3MBTL1 4234/4885CYP1B1 652/4885 |
| US-20240360088-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | PAX8, GAP43, PAX2 | ALDH1A1 1457/4885L3MBTL1 1729/4885CYP1B1 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.