Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914670 | 1.00 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| Hydrochloric Acid SCHEMBL11766454 | 0.98 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL9452505 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL23611530 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL11024622 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL179136 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL30817926 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL29752123 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKDM4EGFER | |
| SCHEMBL9527481 | 0.84 | SLC16A3 (0.49) | ALDH1A1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL11766385 | 0.83 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTKDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605468-B2 | Oxazine-based fluorophore compounds for nerve-specific imaging | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2026-04-21 | — | — | US | disclosed |
| US-20240360088-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-31 | — | — | US | disclosed |
| EP-4367104-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | Oregon Health & Science University (US) | 2024-05-15 | — | — | EP | disclosed |
| CN-117677610-A | Water-soluble neuro-dyes for in vivo neural specific imaging | 俄勒冈健康与科学大学 | 2024-03-08 | — | — | CN | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2023278874-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-05 | — | — | WO | disclosed |
| EP-4093443-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | Oregon Health & Science University (US) | 2022-11-30 | — | — | EP | disclosed |
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| CN-115279423-A | Oxazine-based fluorophore compounds for neurospecific imaging | 俄勒冈健康与科学大学 | 2022-11-01 | — | — | CN | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| WO-2021150979-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021150979-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-29 | — | — | WO | disclosed |
| WO-2020033435-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020023911-A2 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-01-30 | — | — | WO | disclosed |
| US-4423226-A | PHENOXAZINE DYE INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| US-4362873-A | REACTING AN AMINONITROSO WITH AN AMINOPHENOL IN PRESENCE OF ANHYDRIDE | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1982-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | NTRK1, PMP22, GAP43 | ALDH1A1 813/4885L3MBTL1 2675/4885MAPT 636/4885 |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | ALDH1A1 1305/4885L3MBTL1 3166/4885MAPT 1093/4885 |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | GAP43, NTRK1, CHAT | ALDH1A1 1300/4885L3MBTL1 2259/4885MAPT 963/4885 |
| US-12605468-B2 | Oxazine-based fluorophore compounds for nerve-specific imaging | CHRNB2, CHRNB3, CHRNB4 | ALDH1A1 1339/4885L3MBTL1 683/4885MAPT 2554/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | ALDH1A1 822/4885L3MBTL1 1971/4885MAPT 803/4885 |
| US-20240360088-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | PAX8, GAP43, PAX2 | ALDH1A1 1457/4885L3MBTL1 1729/4885MAPT 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.