Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.83 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ITK | Q08881 | 6/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.48 |
| ▸ | CLK2 | P49760 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302284 | 0.91 | EHMT2 (1.00) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL16569005 | 0.87 | EHMT2 (1.00) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL29349799 | 0.87 | EHMT2 (1.00) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL21437350 | 0.76 | EHMT2 (0.65) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL5097272 | 0.74 | EHMT2 (0.62) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL16463990 | 0.73 | EHMT2 (0.64) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL16463988 | 0.73 | EHMT2 (0.77) | EHMT2EHMT1KDM4EHDAC1HDAC8 | |
| SCHEMBL11703846 | 0.72 | KDM4E (1.00) | KDM4EMEN1TSHRKMT2ANPSR1 | |
| SCHEMBL25301895 | 0.71 | ITK (0.59) | EHMT2EHMT1KDM4EMEN1TSHR | |
| SCHEMBL6577802 | 0.71 | NR1H4 (0.62) | MEN1KMT2ALMNATP53HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |