Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.65 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.65 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | ITK | Q08881 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437408 | 0.87 | BACE1 (0.53) | EHMT2EHMT1TSSK1BKMT2AHDAC1 | |
| SCHEMBL25302284 | 0.79 | EHMT2 (1.00) | EHMT2EHMT1LMNAKMT2ANPSR1 | |
| SCHEMBL17915519 | 0.76 | EHMT2 (0.83) | EHMT2EHMT1LMNAKMT2ANPSR1 | |
| SCHEMBL26451957 | 0.76 | EHMT2 (0.50) | EHMT2EHMT1TSSK1BITKCYP2C9 | |
| SCHEMBL16569005 | 0.76 | EHMT2 (1.00) | EHMT2EHMT1LMNAKMT2ANPSR1 | |
| SCHEMBL29349799 | 0.76 | EHMT2 (1.00) | EHMT2EHMT1LMNAKMT2ANPSR1 | |
| SCHEMBL26451963 | 0.75 | BACE1 (0.52) | EHMT2EHMT1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL21437380 | 0.75 | EHMT2 (0.58) | EHMT2EHMT1TP53HSD17B10HDAC1 | |
| Hydrochloric Acid SCHEMBL28512158 | 0.75 | EHMT2 (0.56) | EHMT2EHMT1LMNAKMT2ANPSR1 | |
| SCHEMBL16463988 | 0.74 | EHMT2 (0.77) | EHMT2EHMT1KDM4EHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774740-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | Ohio State Innovation Foundation (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195493-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |