SCHEMBL29349799

SCHEMBL29349799

COC(=O)c1ccc2c(c1)nc(NC(=O)c1ccccc1)n2CCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ EHMT2 Q96KQ7 3/20 1.00
▸ EHMT1 Q9H9B1 1/20 0.81
▸ ITK Q08881 5/20 0.60
▸ KDM4E B2RXH2 3/20 0.58
▸ MEN1 O00255 2/20 0.58
▸ TSHR P16473 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ NPSR1 Q6W5P4 2/20 0.58
▸ USP2 O75604 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ TP53 P04637 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ ADORA2A P29274 6/20 0.56
▸ OPRK1 P41145 2/20 0.56
▸ IRAK4 Q9NWZ3 1/20 0.55
▸ SUV39H1 O43463 1/20 0.53
▸ PRMT1 Q99873 1/20 0.53
▸ RAB9A P51151 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16569005 1.00 EHMT2 (1.00) EHMT2EHMT1ITKKDM4EMEN1
SCHEMBL25302284 0.90 EHMT2 (1.00) EHMT2EHMT1ITKKDM4EMEN1
SCHEMBL17915519 0.87 EHMT2 (0.83) EHMT2EHMT1ITKKDM4EMEN1
SCHEMBL16463988 0.87 EHMT2 (0.77) EHMT2EHMT1ITKKDM4E
SCHEMBL21437365 0.83 EHMT2 (0.71) EHMT2EHMT1ITKKDM4EADORA2A
SCHEMBL8225590 0.80 EHMT2 (0.66) EHMT2EHMT1ITKADORA2AOPRK1
SCHEMBL1467481 0.78 ADORA2A (0.80) EHMT2ITKADORA2A
SCHEMBL5318309 0.77 HDAC6 (0.76) EHMT2EHMT1KDM4ETP53
SCHEMBL24845522 0.76 OPRK1 (0.71) EHMT2ITKKDM4EMEN1TSHR
SCHEMBL24845486 0.76 OPRK1 (0.71) EHMT2ITKKDM4EMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598549-A2 METHODS AND COMPOSITIONS FOR T CELL DIFFERENTIATION The Children's Medical Center Corporation (US) 2025-08-13 — — EP claimed
CN-120053433-A Application of BRD4770 in preparation of medicines for treating and/or preventing DOX-induced cardiomyopathy 天津医科大学 2025-05-30 — — CN claimed
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 — — US claimed
US-20250144056-A1 ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) 2025-05-08 — — US claimed
WO-2025059442-A1 MODULATING PLANT RESPONSES TO STRESS AND GROWTH WITH CHEMICALS REMOTE EPIGENETICS INC. (US) 2025-03-20 — — WO claimed
WO-2024211130-A1 METHODS FOR MODIFYING MEIOTIC RECOMBINATION IN PLANTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-10-10 — — WO claimed
WO-2024199144-A1 NOVEL REAGENT FOR MITIGATING LNP TOXICITY SHANGHAI MOYIN THERAPEUTICS CO., LTD. (CN) 2024-10-03 — — WO claimed
EP-4423254-A1 COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS Memorial Sloan Kettering Cancer Center (US) 2024-09-04 — — EP claimed
US-20240279600-A1 COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-08-22 — — US claimed
WO-2023076554-A9 COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-07-11 — — WO claimed
CN-115397974-A Stromal-free T cell differentiation from human pluripotent stem cells 儿童医疗中心有限公司 2022-11-25 — — CN claimed
US-20220313782-A1 METHODS AND COMPOSITIONS INVOLVING TERT ACTIVATING THERAPIES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-10-06 — — US claimed
WO-2022187682-A2 STROMA-FREE NK CELL DIFFERENTIATION FROM HUMAN PLURIPOTENT STEM CELLS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2022-09-09 — — WO claimed
WO-2022179445-A1 CHEMICAL MICROMOLECULE COMPOSITION FOR CHEMICALLY INDUCING FIBROBLASTS TO BE REPROGRAMMED INTO LUNG STEM CELLS, AND USE THEREOF 海门雨霖细胞科技有限责任公司 2022-09-01 — — WO claimed
CN-114958716-A Method for reprogramming fibroblast into lung stem cell by chemical induction 中国人民解放军海军军医大学第三附属医院 2022-08-30 — — CN claimed
CN-114958726-A Chemical micromolecule composition for reprogramming fibroblast into lung stem cell by chemical induction and application thereof 海门雨霖细胞科技有限责任公司 2022-08-30 — — CN claimed
CN-114344295-A Application of inhibitor BRD4770 in preparing medicine for preventing and treating aortic dissection and pharmaceutical composition thereof 华中科技大学同济医学院附属同济医院 2022-04-15 — — CN claimed
CN-114364392-A Methods and compositions relating to TERT activation therapy 德克萨斯大学系统董事会 2022-04-15 — — CN claimed
US-11298328-B2 Sensorineural hair cell differentiation MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2022-04-12 — — US claimed
EP-3962514-A1 METHODS AND COMPOSITIONS INVOLVING TERT ACTIVATING THERAPIES Board of Regents, The University of Texas System (US) 2022-03-09 — — EP claimed
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