SCHEMBL179202

SCHEMBL179202

O=C(OC(C(F)F)C(F)(F)F)C1CC2C=CC1C2

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.41
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
ESR2 Q92731 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HPGD P15428 1/20 0.34
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13744521 0.84 ALDH1A1 (0.46) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL27009949 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL14410125 0.80 ALDH1A1 (0.46) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL16589158 0.80 ALDH1A1 (0.46) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL954244 0.80 ALDH1A1 (0.46) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL14707472 0.79 ALDH1A1 (0.45) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL13770870 0.78 ALDH1A1 (0.43) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL14134173 0.77 ALDH1A1 (0.41) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL12307730 0.77 ALDH1A1 (0.41) ALDH1A1KDM4ELMNARAB9AKMT2A
SCHEMBL14133970 0.76 ALDH1A1 (0.38) ALDH1A1KDM4ELMNARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8709704-B2 Pattern forming method using developer containing organic solvent and rinsing solution for use in the pattern forming method FUJIFILM CORPORATION (JP) 2014-04-29 US disclosed
US-20120322007-A1 PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM FUJIFILM CORPORATION (JP) 2012-12-20 US disclosed
US-20120056249-A1 INTERLAYER FOR ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
WO-2012028278-A1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
WO-2012028279-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
US-20120056183-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
US-20110229832-A1 PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110229832-A1 PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD RER1, RARA, RARG ALDH1A1 1783/4885KDM4E 3329/4885LMNA 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.