Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17920515 | 1.00 | ADORA1 (0.67) | ADORA1ADORA2AADORA2B | |
| SCHEMBL17920513 | 0.87 | NT5E (0.60) | ADORA1ADORA2AADORA2B | |
| SCHEMBL17920430 | 0.87 | NT5E (0.60) | ADORA1ADORA2AADORA2B | |
| SCHEMBL17920478 | 0.86 | ADORA1 (0.61) | ADORA1ADORA2AADORA2B | |
| SCHEMBL155837 | 0.86 | SLC29A1 (0.75) | ADORA1ADORA2AADORA2B | |
| SCHEMBL155836 | 0.86 | SLC29A1 (0.75) | ADORA1ADORA2AADORA2B | |
| SCHEMBL18571809 | 0.84 | PI4KA (0.62) | ADORA1ADORA2A | |
| SCHEMBL12379237 | 0.84 | PI4KA (0.62) | ADORA1ADORA2A | |
| SCHEMBL20699834 | 0.84 | PI4KA (0.62) | ADORA1ADORA2A | |
| SCHEMBL15865951 | 0.84 | BMPR1B (0.68) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160199491-A1 | Compounds compositions and methods including thermally labile moieties | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160199491-A1 | Compounds compositions and methods including thermally labile moieties | CBR3, ORC3, MSRB3 | ADORA1 484/4885ADORA2A 745/4885ADORA2B 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.