SCHEMBL1792259

SCHEMBL1792259

[CH2]C#CCCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.46
HMGCR P04035 3/20 0.46
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
SLC22A1 O15245 1/20 0.41
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12541573 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3461762 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL313520 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL455197 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3248000 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL12541540 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3281607 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3281239 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL184032 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3461057 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2740724-B1 COMPOUND FOR TREATING CARTILAGE DISORDERS ONO PHARMACEUTICAL CO (JP) 2016-12-28 EP claimed
US-9085523-B2 Compound for treating cartilage disorders ONO PHARMACEUTICAL CO., LTD. (JP) 2015-07-21 US claimed
EP-2740724-A1 COMPOUND FOR TREATING CARTILAGE DISORDERS ONO Pharmaceutical Co., Ltd. (JP) 2014-06-11 EP claimed
CN-115380054-A Amine-modified polymers, controlled radical polymerization for their preparation and their implementation 巴斯夫欧洲公司 2022-11-22 CN disclosed
CN-107249589-B Physiologically active substance-binding block copolymer 日本化药株式会社 2021-06-08 CN disclosed
CN-110372732-B Quebracho-quinoline dimer indole alkaloid compound and application thereof 昆明理工大学 2021-04-30 CN disclosed
CN-108558975-B 12 beta-hydroxy-androstane 4, 14-diene-16-ketone compound and application thereof 昆明理工大学 2021-03-02 CN disclosed
EP-3263107-B1 BLOCK COPOLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE NIPPON KAYAKU KK (JP) 2020-11-11 EP disclosed
CN-108191937-B Polyene androsterone compound and application thereof 昆明理工大学 2020-09-25 CN disclosed
US-10550512-B2 Oil agent for carbon-fiber-precursor acrylic fiber, oil agent composition for carbon-fiber-precursor acrylic fiber, oil-treatment-liquid for carbon-fiber-precursor acrylic fiber, and carbon-fiber-precursor acrylic fiber bundle MITSUBISHI CHEMICAL CORPORATION (JP) 2020-02-04 US disclosed
CN-107075789-B Oil agent for carbon fiber precursor acrylic fiber, composition and treatment liquid thereof, and carbon fiber precursor acrylic fiber bundle 三菱化学株式会社 2020-01-07 CN disclosed
EP-0643119-B1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL CO (JP) 2000-04-26 EP disclosed
US-6030546-A FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-29 US disclosed
EP-0971924-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMINO KETONES Ciba SC Holding AG (CH) 2000-01-19 EP disclosed
EP-0970085-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMINO ALKENES Ciba SC Holding AG (CH) 2000-01-12 EP disclosed
WO-1998041524-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMINO ALKENES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-24 WO disclosed
WO-1998038195-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-03 WO disclosed
WO-1998032756-A1 SUBSTITUTED AMINOALKYLIDENAMINO TRIAZINES AS HERBICIDES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-07-30 WO disclosed
US-5707547-A CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-01-13 US disclosed
EP-0643119-A1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-15 EP disclosed