SCHEMBL184032

SCHEMBL184032

[CH2]C#CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.46
HMGCR P04035 3/20 0.46
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
SLC22A1 O15245 1/20 0.41
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12541573 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3461762 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL313520 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL455197 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3248000 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL12541540 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3281607 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3281239 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL1792259 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3461057 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2147 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232105-A1 PHARMACEUTICAL COMPOSITION FOR INHIBITING OSTEOCLAST GROWTH NATIONAL DEFENSE MEDICAL CENTER (TW) 2012-09-13 US claimed
CN-113939516-B Methods and compositions for targeting protein degradation 珃诺生物医药科技(杭州)有限公司 2024-07-16 CN disclosed
US-12037439-B2 Water-based polymer hydrogel system IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-07-16 US disclosed
EP-4395976-A2 A METHOD OF PRODUCING A BIOACTIVE POLYMER FILAMENT, THE BIOACTIVE POLYMER FILAMENT AND PRINTING METHODS USING THE SAME Agency for Science, Technology and Research (SG) 2024-07-10 EP disclosed
CN-118302289-A Method for producing bioactive polymer filaments, and printing method using same 新加坡科技研究局 2024-07-05 CN disclosed
EP-4394513-A1 LIGHT RESPONSIVE PHOTORESISTS AND METHODS INTEL Corporation (US) 2024-07-03 EP disclosed
US-12018193-B2 Organic-inorganic hybrid bulk assemblies and methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2024-06-25 US disclosed
CN-118244579-A Colored curable composition, color filter and display device 住友化学株式会社 2024-06-25 CN disclosed
CN-118244578-A Colored curable composition, color filter and display device 住友化学株式会社 2024-06-25 CN disclosed
WO-2024123913-A1 KRAS(G12V) INHIBITORS RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) 2024-06-13 WO disclosed
US-5066665-A Cognition activators; alzheimer*s disease WARNER-LAMBERT CO. (US) 1991-11-19 US disclosed
US-4996201-A Alzheimer's disease WARNER-LAMBERT CO. (US) 1991-02-26 US disclosed
EP-0411616-A1 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents WARNER-LAMBERT COMPANY (US) 1991-02-06 EP disclosed
EP-0411615-A1 4-(N-substituted amino)-2-butynyl-1-ureas and thioureas and derivatives thereof as centrally acting muscarinic agents WARNER-LAMBERT COMPANY (US) 1991-02-06 EP disclosed
US-4988688-A Cognitive activators WARNER-LAMBERT COMPANY (US) 1991-01-29 US disclosed
US-4605645-A ANTITUMOR AGENTS TEIJIN LIMITED (JP) 1986-08-12 US disclosed
EP-0081386-B1 5-FLUORO-2'-DEOXYURIDINE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF TEIJIN LIMITED (JP) 1985-05-29 EP disclosed
EP-0081386-A1 5-Fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof TEIJIN LIMITED (JP) 1983-06-15 EP disclosed
US-4008258-A MITICIDE ZOECON CORPORATION (US) 1977-02-15 US disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed