Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.46 |
| ▸ | HMGCR | P04035 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12541573 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL3461762 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL455197 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL3248000 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL12541540 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL3281607 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL3281239 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL184032 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL1792259 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL3461057 | 1.00 | PTPN7 (0.46) | PTPN7HMGCRTSHRTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000070-B1 | SILICON-CONTAINING CHAIN EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2003-09-10 | — | — | EP | claimed |
| EP-0984997-B1 | SILICON-BASED POLYCARBONATES | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-09-18 | — | — | EP | claimed |
| US-6420452-B1 | POLYURETHANES WITH EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-07-16 | — | — | US | claimed |
| EP-1000070-A4 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY LTD (AU) | 2000-06-07 | — | — | EP | claimed |
| EP-1000070-A1 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 2000-05-17 | — | — | EP | claimed |
| EP-0984997-A4 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY LTD (AU) | 2000-03-29 | — | — | EP | claimed |
| EP-0984997-A1 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 2000-03-15 | — | — | EP | claimed |
| WO-1999003863-A1 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1999-01-28 | — | — | WO | claimed |
| WO-1998054242-A1 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1998-12-03 | — | — | WO | claimed |
| EP-4276126-A1 | POLYURETHANE/UREA MATERIALS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2023-11-15 | — | — | EP | disclosed |
| EP-3851469-B1 | POLYURETHANE/UREA MATERIALS | COMMW SCIENT IND RES ORG (AU) | 2023-05-10 | — | — | EP | disclosed |
| CN-110177822-B | Synthesis of polycarbonate siloxane diol | 奥特克国际公开有限公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-3995611-A1 | HIGH THROUGHPUT METHOD FOR CONSTRUCTING AND SCREENING COMPOUND LIBRARY AND REACTION DEVICE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2022-05-11 | — | — | EP | disclosed |
| US-20220119580-A1 | POLYURETHANE/UREA MATERIALS | FOLDAX, INC. | 2022-04-21 | — | — | US | disclosed |
| US-5200412-A | Antiinflammatory agents and antiallergens | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-04-06 | — | — | US | disclosed |
| WO-1993002080-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992018503-A1 | IMIDAZO (4,5-c)PYRIDO DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |
| WO-1992003423-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |