SCHEMBL3281607

SCHEMBL3281607

[CH2]C#CCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.46
HMGCR P04035 3/20 0.46
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
SLC22A1 O15245 1/20 0.41
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12541573 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3461762 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL313520 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL455197 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3248000 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL12541540 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3281239 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL184032 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL1792259 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3461057 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117157081-A Nucleotide derivative with anti-tumor activity, and pharmaceutical composition and application thereof 南京赛弗斯医药科技有限公司 2023-12-01 CN disclosed
US-10550512-B2 Oil agent for carbon-fiber-precursor acrylic fiber, oil agent composition for carbon-fiber-precursor acrylic fiber, oil-treatment-liquid for carbon-fiber-precursor acrylic fiber, and carbon-fiber-precursor acrylic fiber bundle MITSUBISHI CHEMICAL CORPORATION (JP) 2020-02-04 US disclosed
CN-107075789-B Oil agent for carbon fiber precursor acrylic fiber, composition and treatment liquid thereof, and carbon fiber precursor acrylic fiber bundle 三菱化学株式会社 2020-01-07 CN disclosed
EP-3192922-B1 OIL FOR CARBON FIBER PRECURSOR ACRYLIC FIBER, OIL COMPOSITION FOR CARBON FIBER PRECURSOR ACRYLIC FIBER, OIL TREATMENT LIQUID FOR CARBON FIBER PRECURSOR ACRYLIC FIBER, AND CARBON FIBER PRECURSOR ACRYLIC FIBER BUNDLE MITSUBISHI CHEM CORP (JP) 2018-12-12 EP disclosed
US-10072359-B2 Oil agent for carbon fiber precursor acrylic fiber, oil composition for carbon fiber precursor acrylic fiber, processed-oil solution for carbon-fiber precursor acrylic fiber, and method for producing carbon-fiber precursor acrylic fiber bundle, and carbon-fiber bundle using carbon-fiber precursor acrylic fiber bundle MITSUBISHI CHEMICAL CORPORATION (JP) 2018-09-11 US disclosed
US-10005718-B2 Catalyst, and method for producing oxidation product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-06-26 US disclosed
EP-2719823-B1 OIL AGENT FOR CARBON FIBER PRECURSOR ACRYLIC FIBER, PROCESSED-OIL SOLUTION FOR CARBON FIBER PRECURSOR ACRYLIC FIBERS, CARBON FIBER PRECURSOR ACRYLIC FIBER BUNDLE, AND METHOD FOR PRODUCING CARBON FIBER BUNDLE USING CARBON FIBER PRECURSOR ACRYLIC FIBER BUNDLE MITSUBISHI CHEM CORP (JP) 2017-11-08 EP disclosed
US-20170284016-A1 OIL AGENT FOR CARBON-FIBER-PRECURSOR ACRYLIC FIBER, OIL AGENT COMPOSITION FOR CARBON-FIBER-PRECURSOR ACRYLIC FIBER, OIL-TREATMENT-LIQUID FOR CARBON-FIBER-PRECURSOR ACRYLIC FIBER, AND CARBON-FIBER-PRECURSOR ACRYLIC FIBER BUNDLE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-05 US disclosed
EP-2940004-B1 METHOD FOR PRODUCING OXIME SUMITOMO CHEMICAL CO (JP) 2017-09-13 EP disclosed
US-9758502-B2 Dihydropyrone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-12 US disclosed
US-6284784-B1 2-HYDROXYMETHYL DERIVATIVES GEORGETOWN UNIVERSITY 2001-09-04 US disclosed
WO-2001028595-A1 COBALAMIN CONJUGATES USEFUL AS IMAGING AND THERAPEUTIC AGENTS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2001-04-26 WO disclosed
WO-2000062808-A2 COBALAMIN CONJUGATES USEFUL AS ANTITUMOR AGENTS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2000-10-26 WO disclosed
EP-1015427-A1 SUBSTITUTED 2-PYRROLIDINONE ACTIVATORS OF PKC GEORGETOWN UNIVERSITY (US) 2000-07-05 EP disclosed
EP-0643119-B1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL CO (JP) 2000-04-26 EP disclosed
US-6030546-A FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-29 US disclosed
US-5962504-A ACTIVATOR OF PROTEIN KINASE; ANTICANCER AGENT GEORGETOWN UNIVERSITY (US) 1999-10-05 US disclosed
WO-1999012901-A1 SUBSTITUTED 2-PYRROLIDINONE ACTIVATORS OF PKC GEORGETOWN UNIVERSITY (US) 1999-03-18 WO disclosed
US-5707547-A CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-01-13 US disclosed
EP-0643119-A1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10005718-B2 Catalyst, and method for producing oxidation product PPOX, HAO2, SCO2 PTPN7 3325/4885HMGCR 782/4885TSHR 3391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.