SCHEMBL727806

SCHEMBL727806

CCCCCCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
LMNA P02545 3/20 0.32
DNM1 Q05193 6/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4774885 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL14270566 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL5711705 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL1915388 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL11926993 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL1959828 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL727830 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL20477180 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL21114738 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL29766725 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1898 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629328-B2 Oil dispersion solid cosmetic composition containing ascorbic acid and preparation method therefor COSMAX, INC. (KR) 2026-05-19 US claimed
EP-4734912-A2 HIGH SEPARATION DUAL PHASE EYE MAKE-UP REMOVER Mary Kay, Inc. (US) 2026-05-06 EP claimed
EP-4734951-A1 COMPOSITION FOR CONDITIONING THE HAIR L'OREAL (FR) 2026-05-06 EP claimed
US-20260083657-A1 COMPOSITION WITH WHITENING EFFECT AND APPLICATION THEREOF IN COSMETICS YUNNAN BOTANEE BIO-TECHNOLOGY GROUP CO., LTD. (CN) 2026-03-26 US claimed
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2026-03-26 US claimed
EP-4714430-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-25 EP claimed
US-20260069552-A1 Methods of Providing a Cooling Sensation to Skin Afflicted with Eczema KENVUE BRANDS LLC (US) 2026-03-12 US claimed
US-12569533-B2 Bruising and filler compositions and methods for use ALASTIN Skincare, Inc. (US) 2026-03-10 US claimed
US-20260053760-A1 Compositions Suitable for Use on Skin Afflicted with Eczema KENVUE BRANDS LLC (US) 2026-02-26 US claimed
EP-4688908-A2 CROSSLINKED POLYESTER ELASTOMERS, COMPOSITIONS, AND METHODS OF PREPARATION THEREOF Momentive Performance Materials Inc. (US) 2026-02-11 EP claimed
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP claimed
US-20050215072-A1 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2005-09-29 US claimed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO claimed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US claimed
EP-1219289-A2 Cosmetic compositions containing silicone gel Clariant Life Science Molecules (Florida) Inc. (US) 2002-07-03 EP claimed
US-6355724-B1 Cosmetic compositions containing silicone gel CLARIANT LSM (FLORIDA), INC. 2002-03-12 US claimed
US-6258365-B1 SILICONE-HYDROCARBON HYBRID FLUID COMPROSING TRISILOXANE OR TRIS(SILOXY)SILANE COMPOUND; COSMETICS FOR DRY SKIN TREATMENT ARCHIMICA (FLORIDA), INC. 2001-07-10 US claimed
US-6036967-A Mixtures of trimethylsilylated silicas and alkylsiloxanes ARCHIMICA (FLORIDA), INC. (US) 2000-03-14 US claimed
US-5468417-A Silicone containing VOC complaint paint remover DOW CORNING CORPORATION (US) 1995-11-21 US claimed
EP-0657157-A1 Styling aid containing a volatile alkylmethylsilicone DOW CORNING CORPORATION (US) 1995-06-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569533-B2 Bruising and filler compositions and methods for use MYADM, COL14A1, HBG1 TSHR 1278/4885THRB 1333/4885LMNA 358/4885
US-20260069552-A1 Methods of Providing a Cooling Sensation to Skin Afflicted with Eczema CUTA, IDO1, CYP8B1 TSHR 4321/4885THRB 3615/4885LMNA 4693/4885
US-20260083657-A1 COMPOSITION WITH WHITENING EFFECT AND APPLICATION THEREOF IN COSMETICS TYR, NQO1, NAMPT TSHR 2773/4885THRB 3389/4885LMNA 4035/4885
US-12629328-B2 Oil dispersion solid cosmetic composition containing ascorbic acid and preparation method therefor DAGLA, DEGS1, LIPA TSHR 4249/4885THRB 3339/4885LMNA 1401/4885
US-20260053760-A1 Compositions Suitable for Use on Skin Afflicted with Eczema CUTA, OAT, IL17A TSHR 4561/4885THRB 3670/4885LMNA 3617/4885
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE CUTA, TYR, SUN2 TSHR 2955/4885THRB 512/4885LMNA 4254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.