Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011856 | 0.91 | KMT2A (0.36) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL14000182 | 0.90 | KMT2A (0.37) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL14000172 | 0.90 | GAA (0.37) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL14000181 | 0.89 | CNR1 (0.37) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL14000185 | 0.89 | TSHR (0.39) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL2236768 | 0.89 | GAA (0.36) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL14000186 | 0.89 | GAA (0.36) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL6011888 | 0.88 | LMNA (0.34) | KMT2AMAPTMEN1ALDH1A1RAB9A | |
| SCHEMBL14000173 | 0.88 | GAA (0.35) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL14000183 | 0.88 | LMNA (0.35) | KMT2AMAPTMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263671-B1 | AMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION | ASTELLAS PHARMA INC (JP) | 2016-07-20 | — | — | EP | claimed |