Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011856 | 0.93 | KMT2A (0.36) | LMNARAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL2236865 | 0.90 | HDAC1 (0.37) | LMNARAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL17923456 | 0.88 | KMT2A (0.37) | LMNARAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL17923453 | 0.85 | MAPT (0.35) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2240153 | 0.82 | ALDH1A1 (0.39) | RAB9AMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2236534 | 0.81 | HDAC1 (0.38) | ALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL2239299 | 0.79 | HDAC1 (0.36) | LMNAMAPTALDH1A1THRBL3MBTL1 | |
| SCHEMBL21769740 | 0.79 | L3MBTL1 (0.33) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL14000172 | 0.79 | GAA (0.37) | LMNARAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL14000182 | 0.79 | KMT2A (0.37) | LMNARAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652843-A1 | AMIDE DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | claimed |