Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011888 | 0.93 | LMNA (0.34) | KMT2AMEN1CHRM1RAB9ALMNA | |
| SCHEMBL17923456 | 0.91 | KMT2A (0.37) | KMT2AGAAMEN1SMN1; SMN2NPC1 | |
| SCHEMBL2240153 | 0.89 | ALDH1A1 (0.39) | KMT2AUSP2GAAMEN1CHRM1 | |
| SCHEMBL2239299 | 0.83 | HDAC1 (0.36) | CHRM1SMN1; SMN2LMNAL3MBTL1POLB | |
| SCHEMBL2236865 | 0.82 | HDAC1 (0.37) | CHRM1RAB9ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL14000172 | 0.81 | GAA (0.37) | KMT2AGAAMEN1CHRM1SMN1; SMN2 | |
| SCHEMBL14000182 | 0.81 | KMT2A (0.37) | KMT2AGAAMEN1CHRM1SMN1; SMN2 | |
| SCHEMBL14000185 | 0.80 | TSHR (0.39) | KMT2AGAAMEN1SMN1; SMN2NPC1 | |
| SCHEMBL14000181 | 0.80 | CNR1 (0.37) | KMT2AGAAMEN1NPC1RAB9A | |
| SCHEMBL14000186 | 0.79 | GAA (0.36) | KMT2AGAAMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652843-A1 | AMIDE DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | disclosed |