Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17926768 | 0.84 | CYP4F2 (0.35) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL21858204 | 0.84 | GAA (0.36) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL17926749 | 0.81 | GAA (0.34) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL14638396 | 0.76 | GAA (0.36) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL15286836 | 0.71 | RXRA (0.44) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL3338627 | 0.70 | RXRA (0.39) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL20138762 | 0.69 | ALDH1A1 (0.41) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL25958664 | 0.69 | GAA (0.45) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL16100242 | 0.68 | ELANE (0.38) | CYP4F2CYP4A11GAA | |
| SCHEMBL16100241 | 0.68 | ELANE (0.38) | CYP4F2CYP4A11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016113205-A1 | SUBSTITUTED PENTAFLUOROETHYL PYRIMIDINONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-07-21 | — | — | WO | disclosed |