Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27252656 | 0.90 | TLR2 (0.51) | TLR2KMT2ATNF | |
| SCHEMBL30824273 | 0.88 | TLR2 (0.55) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL27252655 | 0.83 | TLR2 (0.48) | TLR2KMT2ATNF | |
| SCHEMBL29400804 | 0.83 | FDFT1 (0.57) | TLR2FDFT1 | |
| SCHEMBL4600701 | 0.83 | FDFT1 (0.57) | TLR2FDFT1 | |
| SCHEMBL800035 | 0.83 | FDFT1 (0.57) | TLR2FDFT1 | |
| SCHEMBL800305 | 0.83 | FDFT1 (0.57) | TLR2FDFT1 | |
| SCHEMBL13108944 | 0.83 | FDFT1 (0.49) | KMT2AHDAC1HDAC2FDFT1 | |
| SCHEMBL29087900 | 0.83 | FDFT1 (0.49) | KMT2AHDAC1HDAC2FDFT1 | |
| SCHEMBL13029965 | 0.83 | FDFT1 (0.49) | KMT2AHDAC1HDAC2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394371-B2 | Antibody-mediated disruption of quorum sensing in bacteria | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-19 | — | — | US | disclosed |