SCHEMBL800035

SCHEMBL800035

CSCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 2/20 0.57
MDM4 O15151 2/20 0.55
TP53 P04637 2/20 0.55
MDM2 Q00987 5/20 0.54
CASP3 P42574 2/20 0.53
TLR2 O60603 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29768618 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL29400804 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL4600701 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL29762010 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL800305 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL29362132 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
Sulfur Dioxide SCHEMBL29187399 0.98 FDFT1 (0.56) FDFT1MDM4TP53MDM2CASP3
SCHEMBL30437543 0.93 MDM2 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL9062110 0.92 MDM4 (0.58) MDM4TP53MDM2CASP3TLR2
SCHEMBL9062116 0.92 MDM4 (0.58) MDM4TP53MDM2CASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-108373496-A Inoxidizability polypeptide GTMGAVGPRG and preparation method thereof 安徽工程大学 2018-08-07 CN claimed
US-20100305182-A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA BLACKWELL HELEN E 2010-12-02 US claimed
EP-1848703-A2 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-10-31 EP claimed
US-20060178430-A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-08-10 US claimed
WO-2006084056-A2 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-08-10 WO claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
CN-118725006-A Process for preparing insoluble peptide 南京金斯瑞生物科技有限公司 2024-10-01 CN disclosed
CN-118620022-A Process for preparing phosphorylated polypeptides 南京金斯瑞生物科技有限公司 2024-09-10 CN disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 EP disclosed
WO-2000001666-A1 C-TERMINAL MODIFIED OXAMYL DIPEPTIDES AS INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES IDUN PHARMACEUTICALS, INC. (US) 2000-01-13 WO disclosed
WO-1998050029-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO disclosed
WO-1994001448-A1 OLIGONUCLEOTIDES MODIFIED WITH CONJUGATE GROUPS PHARMAGENICS, INC. (US) 1994-01-20 WO disclosed
EP-0295316-A2 Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones AMERICAN CYANAMID COMPANY (US) 1988-12-21 EP disclosed
US-4732970-A Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones AMERICAN CYANAMID COMPANY (US) 1988-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305182-A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA AHCYL1, BPHL, AIP FDFT1 180/4885MDM4 974/4885TP53 2008/4885
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP FDFT1 1173/4885MDM4 3741/4885TP53 1141/4885
US-20060178430-A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA AHCYL1, BPHL, AIP FDFT1 180/4885MDM4 974/4885TP53 2008/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 FDFT1 2131/4885MDM4 884/4885TP53 403/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R FDFT1 609/4885MDM4 3559/4885TP53 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.