SCHEMBL4600701

SCHEMBL4600701

CSCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 2/20 0.57
MDM4 O15151 2/20 0.55
TP53 P04637 2/20 0.55
MDM2 Q00987 5/20 0.54
CASP3 P42574 2/20 0.53
TLR2 O60603 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29768618 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL29400804 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL29762010 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL800035 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL800305 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL29362132 1.00 FDFT1 (0.57) FDFT1MDM4TP53MDM2CASP3
Sulfur Dioxide SCHEMBL29187399 0.98 FDFT1 (0.56) FDFT1MDM4TP53MDM2CASP3
SCHEMBL30437543 0.93 MDM2 (0.57) FDFT1MDM4TP53MDM2CASP3
SCHEMBL9062110 0.92 MDM4 (0.58) MDM4TP53MDM2CASP3TLR2
SCHEMBL9062116 0.92 MDM4 (0.58) MDM4TP53MDM2CASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF JIANGXI NORMAL UNIVERSITY (CN) 2023-08-03 US claimed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
CN-110312730-B Cytotoxins and conjugates, uses thereof and methods of preparation 四川科伦博泰生物医药股份有限公司 2024-06-18 CN disclosed
CN-114920851-B Aβ1-42 antigen and use thereof for detecting Aβ1-42 concentration in Alzheimer's patient 福建亿彤生物科技有限公司 2024-05-31 CN disclosed
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
CN-118047737-A Preparation method of amide compound 湖北师范大学 2024-05-17 CN disclosed
US-20240148664-A1 LIPID AND COMPOSITION SOGO PHARMACEUTICAL CO., LTD. (JP) 2024-05-09 US disclosed
CN-114957438-B Human Abeta 1-42 epitope polypeptide for detecting Alzheimer disease and preparation method thereof 福建亿彤生物科技有限公司 2024-04-02 CN disclosed
US-20240076311-A1 METHOD FOR SYNTHESIZING PEPTIDE THIOESTERS AND HEAD-TO-TAIL AMIDE CYCLIC PEPTIDE THEREOF JIANGSU GENSCRIPT BIOTECH CO., LTD. (CN) 2024-03-07 US disclosed
WO-2024043313-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY 三菱ケミカル株式会社 2024-02-29 WO disclosed
US-20060275213-A1 Tumor targeting agents and uses thereof KARYON OY (FI) 2006-12-07 US disclosed
CN-1720258-A Tumor targeting agents and uses thereof KARYON OY (FI) 2006-01-11 CN disclosed
CN-1706865-A Branched polyglycol-amino acid oligopeptide and its active derivative and medicinal composition BEIJING JIANKAI SCI TECH CO LT (CN) 2005-12-14 CN disclosed
EP-1549669-A1 TUMOR TARGETING AGENTS AND USES THEREOF Karyon OY (FI) 2005-07-06 EP disclosed
EP-0986384-A4 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2004-09-15 EP disclosed
WO-2004031221-A9 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-07-08 WO disclosed
WO-2004031221-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 US disclosed
EP-0986384-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 2000-03-22 EP disclosed
WO-1998050029-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148664-A1 LIPID AND COMPOSITION PLIN3, PLIN1, FABP1 FDFT1 322/4885MDM4 2121/4885TP53 1707/4885
US-20240076311-A1 METHOD FOR SYNTHESIZING PEPTIDE THIOESTERS AND HEAD-TO-TAIL AMIDE CYCLIC PEPTIDE THEREOF VIP, CETP, PITHD1 FDFT1 3288/4885MDM4 3923/4885TP53 954/4885
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF ACSL1, ACSL4, WEE1 FDFT1 472/4885MDM4 3883/4885TP53 3299/4885
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R FDFT1 609/4885MDM4 3559/4885TP53 2654/4885
US-20060275213-A1 Tumor targeting agents and uses thereof CCL2, CCL5, SCTR FDFT1 4387/4885MDM4 901/4885TP53 46/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R FDFT1 609/4885MDM4 3559/4885TP53 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.