Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933380 | 0.88 | GRIA1 (0.41) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL17933369 | 0.86 | ACHE (0.36) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL16561831 | 0.85 | ACHE (0.33) | — | |
| SCHEMBL17933331 | 0.83 | ACHE (0.38) | — | |
| SCHEMBL17936290 | 0.82 | GRIA1 (0.37) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL16553693 | 0.80 | GRN (0.36) | — | |
| SCHEMBL12231555 | 0.78 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| SCHEMBL13957320 | 0.78 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| Hydrochloric Acid SCHEMBL21315791 | 0.76 | GRIA1 (0.48) | GRIA1GRIA2GRIA4GRIK5GRIA3 | |
| Hydrochloric Acid SCHEMBL21315788 | 0.76 | GRIA1 (0.48) | GRIA1GRIA2GRIA4GRIK5GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | GRIA1 2508/4885GRIA2 2186/4885GRIA4 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.