Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13547854 | 0.89 | TAAR1 (0.41) | TAAR1LMNAPOLBHTTL3MBTL1 | |
| SCHEMBL12047382 | 0.85 | TAAR1 (0.57) | TAAR1HTTCHRM1CHRM3KDM4E | |
| SCHEMBL14211890 | 0.85 | LMNA (0.40) | TAAR1LMNAPOLBHTTL3MBTL1 | |
| SCHEMBL1788542 | 0.81 | LMNA (0.44) | LMNACYP4F2CYP4A11ACHEBCHE | |
| SCHEMBL11396987 | 0.80 | TP53 (0.46) | TAAR1L3MBTL1BCHETACR1KIF11 | |
| SCHEMBL26030893 | 0.80 | LPL (0.46) | TAAR1HTTACHEBCHEKIF11 | |
| SCHEMBL475558 | 0.80 | TACR1 (0.42) | TAAR1LMNAPOLBHTTL3MBTL1 | |
| SCHEMBL18608715 | 0.80 | TAAR1 (0.56) | TAAR1HTTCHRM1CHRM3KDM4E | |
| SCHEMBL16672574 | 0.80 | TNKS2 (0.45) | LMNACYP4F2CYP4A11ACHEBCHE | |
| SCHEMBL1788540 | 0.80 | LMNA (0.46) | LMNACYP4F2CYP4A11ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207893-A1 | NOVEL CALCIUM MODULATORS | MYOTHERIX, INC. | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207893-A1 | NOVEL CALCIUM MODULATORS | CACNA1E, CASR, CACNA1D | TAAR1 1825/4885LMNA 3962/4885POLB 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.