SCHEMBL475558

SCHEMBL475558

CC(C)(C)c1cccc(CCOCCc2cccc(C(C)(C)C)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ACHE P22303 4/20 0.40
BCHE P06276 2/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
KIF11 P52732 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
IDO1 P14902 2/20 0.37
BACE1 P56817 1/20 0.37
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
MIF P14174 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17523551 0.90 TACR1 (0.39) TACR1TAAR1ACHEBCHEHDAC4
SCHEMBL13547854 0.87 TAAR1 (0.41) TACR1TAAR1ACHEBCHEHDAC4
SCHEMBL1787678 0.81 ACHE (0.44) ACHEBCHEHDAC4HDAC2HDAC8
SCHEMBL17933713 0.80 TAAR1 (0.39) TACR1TAAR1ACHEBCHEHDAC4
SCHEMBL348504 0.80 TACR1 (0.54) TACR1ACHEBCHEHDAC4HDAC2
SCHEMBL1787676 0.80 CYP1A2 (0.43) ACHEBCHEHDAC4HDAC2HDAC8
SCHEMBL14211890 0.79 LMNA (0.40) TACR1TAAR1ACHEBCHEHDAC4
SCHEMBL13639038 0.79 PPARA (0.40) TACR1L3MBTL1
SCHEMBL13639039 0.79 PPARA (0.40) TACR1L3MBTL1
SCHEMBL475557 0.78 TDP1 (0.46) TAAR1ACHEBCHEHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112624996-B Oxazoline derivative containing sulfonate structure, preparation thereof and application thereof in control of phytophagous mites 南开大学 2022-11-11 CN disclosed
EP-2411564-B1 ELECTROCHEMICAL PROCESS FOR PRODUCING 3-TERT-BUTYLBENZALDEHYDE-DIMETHYLACETAL BASF SE (DE) 2017-05-10 EP disclosed
CN-104926623-A Preparation method for etoxazole intermediate 3-tert-butylphenylethylether SHANGHAI CAC CHEMICAL CO LTD 2015-09-23 CN disclosed
CN-104926623-A Preparation method for etoxazole intermediate 3-tert-butylphenylethylether SHANGHAI CAC CHEMICAL CO LTD 2015-09-23 CN disclosed
CN-104557480-A Synthetic method of 3-tert-butylphenylethylether SHANGHAI SHENGNONG PESTICIDE CO LTD 2015-04-29 CN disclosed
CN-104557480-A Synthetic method of 3-tert-butylphenylethylether SHANGHAI SHENGNONG PESTICIDE CO LTD 2015-04-29 CN disclosed
CN-104557480-A Synthetic method of 3-tert-butylphenylethylether SHANGHAI SHENGNONG PESTICIDE CO LTD 2015-04-29 CN disclosed
CN-103113318-A New etoxazole compound, preparation method and acaricidal activity thereof NANJING UNIVERSITY OF TECHNOLOGY 2013-05-22 CN disclosed
EP-2411564-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2012-02-01 EP disclosed
WO-2010108874-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2010-09-30 WO disclosed