Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 5/20 | 0.43 |
| ▸ | BACE1 | P56817 | 12/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873747 | 0.80 | ENPEP (0.52) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL31089740 | 0.79 | ENPEP (0.55) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL5194261 | 0.79 | ENPEP (0.55) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL19794 | 0.78 | BACE1 (0.52) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL17930179 | 0.78 | CASP3 (0.48) | ENPEPBACE1BACE2CASP1CASP3 | |
| SCHEMBL18293548 | 0.78 | ENPEP (0.48) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL31315589 | 0.77 | BACE1 (0.47) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL29904046 | 0.77 | BACE1 (0.51) | ENPEPBACE1BACE2CTSD | |
| SCHEMBL16597491 | 0.76 | BACE1 (0.45) | ENPEPBACE1BACE2CTSDCASP1 | |
| SCHEMBL2564476 | 0.76 | BACE1 (0.45) | ENPEPBACE1BACE2CTSDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160206758-A1 | DICHROMIC FLUORESCENT COMPOUNDS | WASHINGTON UNIVERSITY | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206758-A1 | DICHROMIC FLUORESCENT COMPOUNDS | DCAF15, DDT, DCAF1 | ENPEP 3666/4885BACE1 2290/4885BACE2 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.