SCHEMBL17934754

SCHEMBL17934754

O=C(O)c1ccc(-c2c3nc(c(-c4ccccc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5ccc2[nH]5)CC4)C=C3)cc1

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.75
▸ CYCS P99999 4/20 0.73
▸ ENPP2 Q13822 1/20 0.47
▸ ABCG2 Q9UNQ0 1/20 0.44
▸ STAT3 P40763 1/20 0.43
▸ STAT1 P42224 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ GLA P06280 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ TERT O14746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15258312 0.96 TOP1 (0.81) TOP1CYCSENPP2ABCG2KDM4E
SCHEMBL25394852 0.91 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL483511 0.91 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL16418477 0.91 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL25395869 0.91 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL29556585 0.91 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL17934752 0.90 TOP1 (0.60) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL19640818 0.90 CYCS (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL6693557 0.90 TOP1 (0.88) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL6686149 0.90 TOP1 (0.88) TOP1CYCSENPP2ABCG2STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3038619-B1 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION PCI BIOTECH AS (NO) 2023-10-04 — — EP disclosed
EP-3185901-B1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2023-10-04 — — EP disclosed
US-20170252441-A1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2017-09-07 — — US disclosed
US-20160206725-A1 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION PCI BIOTECH AS (NO) 2016-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170252441-A1 COMPOUND AND METHOD CSF3R, IL2, IL5 TOP1 2013/4885CYCS 2836/4885ENPP2 226/4885
US-20160206725-A1 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION TLR9, TLR3, TLR1 TOP1 3662/4885CYCS 4582/4885ENPP2 282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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