Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762005 | 0.81 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL18997999 | 0.80 | HSP90AA1 (0.48) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL11403516 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL17935432 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL6379173 | 0.77 | KDM4E (0.97) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL18550512 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL17935215 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| Dibemethine SCHEMBL10542007 | 0.73 | ALDH1A1 (0.70) | KDM4EALDH1A1KMT2AUSP2GAA | |
| Dibemethine SCHEMBL276863 | 0.73 | ALDH1A1 (0.70) | KDM4EALDH1A1KMT2AUSP2GAA | |
| SCHEMBL12060877 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016113169-A1 | TETRA- AND PENTASUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-07-21 | — | — | WO | disclosed |