Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.54 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17940142 | 0.89 | CYP3A4 (0.68) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL17943841 | 0.88 | KDM4E (0.52) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL25229668 | 0.85 | CSNK2A2 (0.61) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL17944028 | 0.84 | TP53 (0.70) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL28424508 | 0.83 | MAPT (0.64) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL30175553 | 0.82 | MAPT (0.62) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL6176954 | 0.82 | KDM4E (0.68) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL17944301 | 0.81 | KDM4E (0.46) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL10887195 | 0.79 | MEN1 (0.58) | KDM4ECYP3A4MEN1KMT2AHSD17B10 | |
| SCHEMBL17949892 | 0.79 | KDM4E (0.43) | KDM4ECYP3A4MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2016123141-A1 | CARBON MONOXIDE RELEASING MOLECULES AND ASSOCIATED METHODS | BERREAU LISA M (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016123141-A1 | CARBON MONOXIDE RELEASING MOLECULES AND ASSOCIATED METHODS | BERREAU LISA M (US) | 2016-08-04 | — | — | WO | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | MB, CORO1C, CYCS | KDM4E 1691/4885CYP3A4 698/4885MEN1 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.