Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.57 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.57 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424508 | 0.99 | MAPT (0.64) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL6176954 | 0.91 | KDM4E (0.68) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL25229668 | 0.86 | CSNK2A2 (0.61) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL6176182 | 0.85 | CSNK2A2 (0.55) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17786624 | 0.82 | MAPT (0.52) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17940164 | 0.82 | KDM4E (0.56) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL10887195 | 0.80 | MEN1 (0.58) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL68189 | 0.78 | TTR (0.83) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL11439145 | 0.78 | TTR (0.59) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL8551049 | 0.77 | CSNK2A2 (0.52) | MAPTKDM4EMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393460-B | Zinc coordination compound of flavone derivative and preparation method and application thereof | 鲁东大学 | 2023-01-17 | — | — | CN | disclosed |