Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | RET | P07949 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.61 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.61 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | CASP1 | P29466 | 4/20 | 0.55 |
| ▸ | CASP7 | P55210 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17940142 | 0.88 | CYP3A4 (0.68) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL17943841 | 0.85 | KDM4E (0.52) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL25239822 | 0.84 | TP53 (0.67) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL17940164 | 0.84 | KDM4E (0.56) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL17943840 | 0.83 | TP53 (0.51) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL10037935 | 0.82 | TP53 (1.00) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL17940134 | 0.82 | MAPT (0.49) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL17944015 | 0.81 | KDM4E (0.57) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL4650064 | 0.80 | MAPT (1.00) | TP53LMNARETTSHRALOX12 | |
| SCHEMBL15676210 | 0.80 | MAPT (0.79) | TP53LMNARETTSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | MB, CORO1C, CYCS | TP53 1292/4885LMNA 3783/4885RET 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.